Israeli officials gave an update Saturday on the conflict with Gaza after an Israeli airstrike destroyed a building housing offices of the AP and other media outlets. Source

The 146th running of the Preakness Stakes gets underway Saturday. After some speculation, Kentucky Derby winner Medina Spirit has been cleared to run, days after failing a post-race drug test. Gus Garcia-Roberts, a sports-focused investigative reporter with the Washington Post, joined CBSN’s Lana Zak to discuss drug use in the horse racing industry, and what the future of the sport looks like following recent scandals. Source

Americans are receiving mixed messages about wearing masks. The CDC announced those who are fully vaccinated do not need to wear masks in most situations, leaving it up to states to do what they will with that guidance. Politico health care reporter Alice Ollstein spoke with CBSN’S Lana Zak about the potential public health impact. Source

If ever there was a time to want to be driving an electric car, it may have been last week — after the Colonial Pipeline cyberattack forced the company to take some of its systems offline. Source

Fighting has intensified between the Israeli military and Hamas militants in Gaza. The Israeli Defense Forces conducted an airstrike on a prominent high-rise building in Gaza City on Saturday. The bombing leveled the structure which had housed several media outlets including the Associated Press and Al Jazeera. CBS News Foreign Correspondent, Imtiaz Tyab joins from Tel Aviv to discuss the escalating violence. Source

CDC guidance prompts states, retail stores to lift mask mandates; Maya Angelou and Sally Ride to appear on coinage series honoring trailblazing American women Source

The first two nights of Passover looked and felt different for millions of Jews around the world this year as many families celebrated via webcam. Rabbi Sharon Kleinbaum of New York City’s Congregation Beit Simchat Torah joins CBSN’s Tanya Rivero for a closer look at the special meaning of the holiday this year. Source

It came hours after another Israeli air raid on a densely populated refugee camp killed at least 10 Palestinians from an extended family, mostly children. Source

A former Florida tax collector has agreed to help the Justice Department’s investigation into Congressman Matt Gaetz. Joel Greenberg admitted Friday he paid an underage girl to have sex with him and other unidentified men. Greenberg is expected to plead guilty to six federal charges next week. Major Garrett reports on what this could mean for Gaetz. Source

The violence between Israel and the Islamic militant group Hamas in Gaza is not letting up. On Saturday morning, an Israeli airstrike on a house in Gaza City killed at least 10 people, some of them children. That’s the highest number of fatalities in a single attack since the conflict began less than a week ago. While some of the most intense assaults have been in Gaza and southern Israel, a much broader offensive is taking shape. Imtiaz Tyab is in Tel Aviv with the latest. Source