Identical twins Keith and Kenny Lucas have found plenty of outlets for their talents, from the comedy club circuit to the big screen in the film “22 Jump Street” and even an animated series on Fox. But their latest effort has been quite a departure and a remarkable success. This year, they scored an Oscar nomination for their screenplay “Judas and the Black Messiah.” “CBS This Morning: Saturday” co-host Michelle Miller spoke to the brothers. Source

Martin Desmond Roe and Travon Free, co-directors of “Two Distant Strangers,” spoke to Jericka Duncan about their Oscar-nominated film. “Two Distant Strangers” is a drama about one man’s never-ending confrontations with the same deadly series of events. Source

The number of coronavirus deaths worldwide has topped 3 million, with cases on the rise. In the United States, despite 40% of Americans receiving at least one dose of the COVID-19 vaccine, the country is now seeing a rise in coronavirus cases. Experts say new variants of the virus are fueling the latest surge. Tom Hanson reports. Source

According to a new study, patients with advanced colon cancer found on the left side survived longer than those with tumors on the right side of the colon. The co-author of the study says there is now evidence to prove doctors should think differently about patients depending on where their cancer grew. Dr. Jon LaPook has more. Source

CBS News examines the pathway from pain to prescription painkillers and addiction, while opioid related overdose deaths continue to climb. Source

CBS News contributor and former “Face the Nation” moderator Bob Schieffer joins “CBS This Morning” to discuss what might become a tight general election race this fall and what he thinks of Donald Trump’s foreign policy. Source

Middle Kids return to Saturday Sessions after releasing their latest album, “Today We’re The Greatest.” The indie band from Australia came together in 2016 to rave reviews and even a shoutout from Elton John. The band joins “CBS This Morning: Saturday” to perform their song “Cellophane.” Source

Vice President Joe Biden reflects on his career and writes a letter to his 12-year-old self. Watch the full piece Thursday on “CBS This Morning.” Source

The Obama administration is issuing laws that give over 4 millions workers overtime; Google begins their annual I/O conference with plenty of new tech; and Ben & Jerrys’ new flavor is politically motivated. CBS News MoneyWatch’s Jill Wagner has the day’s business headlines on CBSN. Source

Rose Byrne, who made her comedic name with Kristen Wiig in “Bridesmaids,” is reprising her role as Kelly Radner in the “Neighbors” sequel with Seth Rogan. Byrne joins “CBS This Morning” to discuss “Neighbors 2: Sorority Rising” and why she created her production company. Source