Afghanistan’s capital was thrown into chaos Wednesday by one of its worst terror attacks in years. A huge suicide car bomb killed at least 80 people and injured hundreds more. The explosion went off just outside an area known for its intense security near the presidential palace as well as a large number of embassies. Debora Patta reports. Source

The FDA expanded the approved uses for an immunotherapy drug that has successfully treated certain lung cancers and melanoma. The treatment that triggers the body’s own defense system to fight cancer was used by former President Jimmy Carter, who reported a few months later he was cancer-free. Dr. David Agus joins “CBS This Morning” to discuss the cancer treatment. Source

COVID-19 vaccine hesitancy concerns, warnings about new variants; Chef Donna Lennard on history of Il Buco Source

Some action movie fans expect this summer to be a great time for strong female characters. Fandango correspondent Chris Witherspoon joined CBSN to discuss what movies to check out. Source

Oscar-winning actress Melissa Leo stars in the new Showtime series, “I’m Dying Up Here,” based on the Los Angeles comedy scene in the 1970s. Jim Carrey, who got his start back then, is the executive producer. Leo joins “CBS This Morning” to discuss her role as Goldie, the owner of a famed comedy club that makes or breaks young stand-up comics. Source

Florida’s rainy season is ramping up, and so is the threat of mosquitoes carrying the Zika virus. More than 5,000 people in the U.S. have reported having Zika since last year. Most people caught it overseas, but nearly all 224 locally-transmitted cases in 2016 happened in Florida. Manuel Bojorquez reports. Source

John F. Kennedy was sworn in as the 35th president on January 20, 1961 Source

John F. Kennedy, then a Massachusetts senator, and his new wife, Jacqueline Kennedy Onassis, spoke with CBS News’ Edward R. Murrow in 1953. Source

The body of a 79-foot-long blue whale that washed ashore in Northern California had injuries consistent with being struck by a ship, CBS San Francisco reports. Source

In times of anxiety, people search for words of hope. Many reached back deep into their childhood, to the words of Mr. Rogers. Entertainment Weekly senior writer Anthony Breznican shares with Steve Hartman a story of inspiration about watching “Mister Rogers’ Neighborhood” helped him — and how a chance encounter in an elevator with Fred Rogers helped more. Source