Millions stuck with their Thanksgiving plans despite a warning from the Centers for Disease Control and Prevention for travelers to just stay home because of the coronavirus pandemic. More than 2,200 COVID-related deaths were reported in the U.S. on the day before Thanksgiving, the highest one-day toll in more than six months. CBS News correspondent Adriana Diaz reports from Chicago, and Dr. Shoshana Ungerleider, an internal medicine physician at California Pacific Medical Center, joined CBSN to discuss. Source

Several top Democrats slammed President Trump for pardoning former national security adviser Michael Flynn while many Republicans praised the controversial move. Flynn pleaded guilty twice to lying to the FBI about his conversations with top Russian diplomats during the 2016 election. CBS News senior investigative correspondent Catherine Herridge joined CBSN to explain the latest developments and what’s next for Flynn. Source

AstraZeneca and Oxford University acknowledged a manufacturing error that raised questions about preliminary results of their experimental COVID-19 vaccine. Source

The U.S. reported the deadliest day in the coronavirus pandemic since early May with more than 2,200 deaths. CBS News medical contributor Dr. David Agus joins “CBS This Morning” to discuss Thanksgiving concerns as millions of Americans travel for the holiday. He also comments on the AstraZeneca-Oxford coronavirus vaccine candidate. Source

Senator David Perdue sold and bought stocks as the coronavirus began ravaging the United States. Source

The Trump administration is warning of being on the “cusp” of a “major influx” of unauthorized migration of children to the U.S. southern border. Source

The Bidens said in an op-ed that they “are temporarily letting go of the traditions we can’t do safely.” Source

Buyer beware: Not everything is at its best price as the holiday season revs up after Thanksgiving. Source

Job losses may accelerate, experts warn, if Washington politicians fail to pass a stimulus bill by the end of the year. Source

The U.S. suffered its deadliest day in the coronavirus pandemic in more than six months. Also, President Trump has pardoned his former adviser Michael Flynn. All that and all that matters in today’s Eye Opener. Your world in 90 seconds. Source